Clinical trials
Alcohol Abuse clinical trials
Below are recruiting alcohol abuse clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07216872Recruiting
Deep TMS to reduce heavy drinking in alcohol use disorder
This trial tests a non-invasive brain stimulation device (Deep TMS) to help people with alcohol use disorder reduce or stop heavy drinking. It uses magnetic pulses to target brain areas linked to addiction.
Tuscaloosa, AlabamaAges 18–86 - NCT06262958Recruiting
Early help for teen alcohol and substance issues
This study looks at early help for alcohol and substance use in teenagers. The goal is to see if early support can improve outcomes for young people who have been treated at a psychiatric clinic.
KuopioAges 14–19 - NCT05855031Recruiting
Liver care support for people getting alcohol-use treatment
This trial looks at liver-focused care for people receiving outpatient treatment for alcohol dependence or alcohol-related harmful drinking. It may help by checking and improving how your liver health is supported while you stay in alcohol-use treatment.
KøgeAges 18–110 - NCT06265506Recruiting
Virtual Reward Program for Cutting Back on Heavy Drinking
This study tests a virtual program that rewards you for reducing heavy drinking. You'd use a phone app, check in via Zoom, and get a glimpse into your drinking patterns through a blood test. It might be a good fit if you want to cut back on heavy drinking without going to an in-person clinic.
Spokane, WashingtonAges 18 years+ - NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT06415721Recruiting
TMS guided by brain scans for alcohol use disorder
This study uses a brain stimulation technique called TMS combined with MRI scans to treat alcohol use disorder. It aims to see if targeting specific brain connections can help reduce drinking.
Palo Alto, CaliforniaAges 25–75 - NCT03294460RecruitingPhase 1
Genetic study of smoking and alcohol response in healthy adults
This Phase 1 study tests whether certain genes linked to nicotine receptors affect how people feel and respond to alcohol. It also compares alcohol responses in smokers versus non-smokers using brain imaging (MRI) and alcohol-earning/reward tasks, aiming to better understand why some people may crave alcohol more than others.
Bethesda, MarylandAges 21–60 - NCT05619185Recruiting
Online program to help couples reduce risky drinking
This study tests an adaptive (tailored) online program to help service members and their partners cut down risky alcohol use. It also focuses on whether couples can practice healthier communication and coping skills while feeling safe together.
Palo Alto, CaliforniaAges 18 years+ - NCT02108080Recruiting
Study of brain imaging in people with alcohol use disorder
This study collects natural history information and brain imaging (MRI) using an imaging instrument to compare people with alcohol use disorder and people without. It may help researchers understand how brain imaging works in real-world participants and how it relates to alcohol-related health.
Bethesda, MarylandAges 18 years+ - NCT05677321Recruiting
Study how taste and smell differ in alcohol use disorder
This study compares how people with alcohol use disorder and people without it experience taste and smell. It also checks brain activity during taste/smell testing to understand individual differences that may be linked to alcohol use.
Bethesda, MarylandAges 18–65 - NCT06405607RecruitingPhase 2
Psilocybin vs Ketamine for Alcohol Use Disorder Trial
This trial tests two psychedelic-assisted therapies, psilocybin and ketamine, to see which works better for reducing heavy drinking in people with alcohol use disorder (AUD). You'll receive either drug along with counseling, and the study monitors safety closely.
Iowa City, IowaAges 21–65 - NCT07325266RecruitingPhase 2
Testing apremilast for alcohol use disorder
This study tests whether a pill called apremilast can help reduce drinking in people with alcohol use disorder. You'll take the medication and attend regular visits to see how it affects your alcohol cravings and use.
Los Angeles, CaliforniaAges 21 years+ - NCT02231840Recruiting
Study of how alcohol use changes over time
This study follows people over time to understand how alcohol use develops and changes. It may help researchers learn what factors are linked to changes in drinking, and it involves genetic testing and an MRI scan.
Bethesda, MarylandAges 18–100 - NCT04946851Enrolling by invitation
Alcohol use study for adults who join the NIAAA screening
This study uses a brain-and-behavior “assessment” (neuroclinical testing) to better understand addiction. You may be tested only if you are an adult and are enrolled in the NIAAA screening program, and you cannot join if you are acutely intoxicated.
Bethesda, MarylandAges 18–99 - NCT02108054Recruiting
Building and testing tasks to measure brain and movement
This study helps create and test simple tasks that measure brain function and movement in people with different backgrounds. It may help researchers better understand how the brain and body work, which can improve future alcohol-related treatments.
Bethesda, MarylandAges 18–65 - NCT07046819RecruitingPhase 2
Tirzepatide for liver disease linked to alcohol use
This trial tests if tirzepatide, a medication that helps with weight and blood sugar, can improve liver health in people with alcohol use disorder who also have fatty liver disease. It aims to reduce liver fat and related risks.
Bethesda, MarylandAges 21–100 - NCT04391816Recruiting
Study of how alcohol use changed during the COVID-19 pandemic
This study follows people over time to understand how the COVID-19 pandemic affected alcohol use and related health or behaviors. You may help by answering short surveys by phone or online on a regular schedule.
Bethesda, MarylandAges 18–100 - NCT06269627RecruitingPhase 4
Brain activity study for alcohol use treatment
This trial tests how the medication acamprosate affects brain activity in people with moderate to severe alcohol use disorder. It may help researchers understand how this treatment works.
Bethesda, MarylandAges 21–65 - NCT06484075RecruitingPhase 1/Phase 2
Suvorexant for alcohol use disorder: brain effects
This study tests whether the sleep medication suvorexant can help people with alcohol use disorder by looking at its effects on brain activity. Participants will stay in the hospital for about a month, take suvorexant or a placebo, and have brain scans.
Bethesda, MarylandAges 18–75 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT06819189RecruitingPhase 1
How a gene affects alcohol response
This study looks at how a specific gene (ZIP8) affects the way people respond to alcohol. You'll have MRI brain scans and may be given alcohol to see how your brain reacts. It's for healthy right-handed adults of European ancestry who have some drinking experience.
Bethesda, MarylandAges 21–60 - NCT07281261Recruiting
Nerve stimulation for alcohol use disorder
This study tests whether a mild nerve stimulation device (tAN) can help reduce alcohol cravings and withdrawal. It's for people with moderate to severe alcohol use disorder who are going through withdrawal and do not use tobacco.
Houston, TexasAges 18–64 - NCT04781322RecruitingPhase 1
Study drug to reduce LDL cholesterol effects in heavy drinkers
This Phase 1 study tests how safe a cholesterol-lowering antibody (alirocumab) is in people who drink heavily but are not seeking alcohol treatment. It also looks at early drug effects in the body to see how it might change cholesterol-related signals.
Bethesda, MarylandAges 21–65 - NCT07559500RecruitingPhase 1
Study of tirzepatide for alcohol use disorder
This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.
Bethesda, MarylandAges 21–65
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Alcohol Abuse trials by city
Studies with a site in or near these metro areas.
Alcohol Abuse trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for alcohol abuse?
- Yes. Clin2 currently lists 44 recruiting alcohol abuse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol abuse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol abuse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.