Balloon treatment for leg artery blockages with calcium
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have leg pain or wounds (Rutherford category 2-5)
- You have a severe blockage (more than 70%) or complete closure in your thigh or knee artery
- You have at least one open artery below the knee to allow blood flow to the foot
- Your life expectancy is more than 2 years
- You have moderate to severe calcium buildup in the blocked area
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new device that uses sound waves (lithotripsy) to break up hard calcium deposits in leg arteries for people with peripheral artery disease (PAD). It aims to safely open blocked arteries and improve blood flow, potentially reducing pain and improving walking.
This trial tests whether a drug-coated balloon can better reopen blocked arteries in the lower leg (below the knee). It may help keep blood flow open and reduce the chance the blockage comes back, after a procedure to cross and open the narrowed area.
This study tests a balloon coated with medication to open blocked arteries below the knee in people with severe leg pain or tissue loss (critical limb-threatening ischemia). The goal is to see if it helps improve blood flow and save the leg.
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
This trial tests a special preparation method (breaking up calcium) plus a Supera stent versus standard preparation plus stenting for people with severe calcium buildup and long blockages in the thigh or behind-the-knee artery. It aims to see which approach works better for opening the artery and keeping it open.
This study compares two ways of preparing a blocked leg artery before using a drug-coated balloon to open it. It aims to see if using a special scoring balloon helps the treatment work better.
Hear when a new Chronic Limb-Threatening Ischemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.