Study on blood thinners and artery health for small vessel stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether a combination of antiplatelet drugs and artery-stabilizing medication can improve recovery after a small stroke caused by damage to tiny blood vessels in the brain. It may help prevent further strokes and support healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 79 years old.
- You had a small stroke in a deep part of the brain in the last 3 weeks, or you have white matter changes seen on a brain scan (rated as moderate to severe).
- You do not have symptoms like trouble speaking, recognizing objects, or vision loss in one side of your visual field.
- You can walk on your own or with some help (disability score of 4 or less).
- Your main brain arteries are not significantly blocked (no stenosis of 30% or more in neck or vertebra arteries related to your stroke).
- You do not have a heart condition that requires blood thinners for conditions like atrial fibrillation.
- You have no history of bleeding in the brain, active stomach ulcers, or bleeding problems.
- You are not pregnant, planning pregnancy, or breastfeeding, and you are willing to use birth control during the study.
- You can have an MRI scan and are willing to attend follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a combination of blood pressure control and antiplatelet therapy for people whose stroke symptoms are getting worse. It is looking for those without a large brain artery clot or heart-related cause.
This study looks at how severe narrowing of brain arteries may affect memory and thinking over time. It involves people who have had a mini-stroke or mild stroke and aims to understand the changes in cognitive function.
This trial tests whether a combination of two or three anti-platelet medicines (like aspirin, clopidogrel, or cilostazol) is safe and works better than one alone for people who had a stroke from a narrowed artery. The goal is to prevent another stroke.
This trial tests a combination of two blood thinners (antiplatelet drugs) to see if they work better than one in people who had a mild stroke caused by a narrowed artery in the brain. If you had a recent first stroke and are otherwise healthy, you may be able to join.
This study tests if combining the blood thinner clopidogrel with either atorvastatin or rosuvastatin (both cholesterol-lowering drugs) works better for people who have had a mild first-time stroke in the small blood vessels of the brain. The goal is to find a safe and effective treatment regimen.
This trial tests whether cilostazol, a medication that helps keep blood flowing, can prevent another stroke and slow down disease progression in people who have had a recent stroke caused by small vessel disease. It aims to stop the brain damage from getting worse.
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