Clin2
NCT05287451Possibly a fitRecruiting

Tube removal now, ovaries later for high cancer-risk women

Ovarian CancerFallopian Tube Cancer

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study looks at the safety of removing your fallopian tubes first (RRS) and delaying ovary removal (oophorectomy) to lower cancer risk. It focuses on women who carry certain inherited gene changes, and may help avoid earlier menopause for some people.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are premenopausal (still having periods), not postmenopausal for 12 months
  • You have a known inherited gene mutation (BRCA1, BRCA2, BRIP1, RAD51C, PALB2, and/or RAD51D)
  • You are in the study age range based on your specific gene (roughly 25–50)
  • You want fallopian tube removal now and do not need the tubes for natural pregnancy later (IVF is OK)
  • You still have at least one fallopian tube
  • You are willing and able to sign consent (and are able to understand the study)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04294927Recruiting
Tube removal first, then ovaries later for high-risk women

This study looks at whether removing the fallopian tubes first, and the ovaries later, is safe for women with certain inherited gene mutations that raise ovarian cancer risk. It may help you understand a prevention approach when you’re considered high risk and have finished having children.

Chicago, Illinois
NCT07532434Recruiting
Risk-Reducing Surgery for Hereditary Ovarian Cancer

This study follows women who carry gene mutations that increase ovarian cancer risk to understand how preventive surgery affects their health, quality of life, and peace of mind. Researchers will track your outcomes over 3 years to help inform future treatment decisions for others at similar risk.

Beijing, Beijing Municipality
NCT07761416Not yet recruiting· Early Phase 1
Fallopian tube removal during weight loss surgery to prevent ovarian cancer

This study looks at removing the fallopian tubes during weight loss surgery (also called bariatric surgery) to lower the risk of ovarian cancer. This is done as a preventive measure and is being tested to see if it is safe and feasible.

NCT00005095Recruiting
Ovarian cancer risk study: specimens and health data

This study collects tissue samples and medical information from people at higher risk for ovarian cancer or undergoing gynecologic surgery. Researchers use this data to develop better ways to detect and prevent ovarian cancer early.

Chicago, Illinois
NCT05200260Recruiting· Phase 2
Surgery plus maintenance medicines for advanced ovarian cancer

This trial checks whether having surgery to remove as much tumor as possible, followed by ongoing targeted treatment, helps people with advanced ovarian (and related) cancers live longer and/or control cancer better. It specifically uses tumor-testing results to match patients and then continues treatment after surgery.

Foshan
NCT06312124Recruiting
Fallopian tube removal to prevent ovarian cancer

This study looks at removing fallopian tubes during other planned surgeries to help prevent ovarian cancer. You may be able to join if you are at least 45 years old, are female or assigned female at birth, and are having non-gynecologic surgery (like gallbladder or hernia repair).

Baltimore, Maryland

Hear when a new Ovarian cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.