Clin2
NCT06728618Possibly a fitNot yet recruiting

Combination therapy for recurrent mouth and throat cancer

Oral Squamous Cell Carcinoma (OSCC)Oropharyngeal Squamous Cell Carcinoma (SCC)Resectable Oral and Oropharyngeal Squamous Cell CarcinomaRecurrent Oral and Oropharyngeal Squamous Cell Carcinoma

Part of Cancer clinical trials.

This trial tests a combination of drugs (tislelizumab, cetuximab, and chemotherapy) before and after surgery for people whose mouth or throat cancer has returned after previous treatment. The goal is to see if this approach can help shrink or control the cancer and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
28 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have been diagnosed with squamous cell carcinoma of the mouth or throat that has come back after at least 16 weeks since your last treatment.
  • You are between 18 and 75 years old.
  • You are generally well enough to carry out daily activities (ECOG score 0 or 1).
  • A doctor believes you are able to have surgery to remove the cancer.
  • You have not had certain immune therapies (like anti-PD-1 or anti-PD-L1) before.
  • You have no active infections, liver problems, or other serious health conditions.
  • You agree to use effective birth control during the study and for 12 months after.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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