Testing drug combo before throat cancer surgery
Part of Cancer, Ear, nose & throat clinical trials.
This trial tests a new combination of drugs (an immunotherapy called a PD-1 inhibitor, cetuximab, and platinum chemotherapy) given before surgery for advanced throat cancer that requires removing the voice box. The goal is to see if this treatment shrinks the tumor and improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of throat cancer called hypopharyngeal squamous cell carcinoma.
- You are between 18 and 75 years old.
- Your cancer is locally advanced, meaning it has not spread far, but it requires surgery to remove your voice box (total laryngectomy).
- You have not had any previous treatment for this cancer.
- You are in good general health, able to do most daily activities, and your organs are working well.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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