Stomach procedure to maintain weight loss after GLP-1s
Part of Hormones & metabolism clinical trials.
This study is for people who have lost weight using semaglutide or tirzepatide and are stopping that medication. It tests a stomach procedure (called mucosal ablation) to see if it can help you keep the weight off after stopping the drug.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your age is between 21 and 65 years old.
- Your body mass index (BMI) is between 30 and 45. If you need to calculate your BMI, we can help.
- You have lost at least 10% of your total body weight while taking either semaglutide (brand names like Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) specifically for obesity treatment.
- You have been on a steady, unchanging dose of semaglutide or tirzepatide for at least 12 weeks.
- You have recently stopped or plan to stop taking semaglutide or tirzepatide within 24 weeks (about 5.5 months) before the procedure.
- You do not have type 1 or type 2 diabetes (your blood sugar should be normal).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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