Study testing mRNA vaccine for multiple sclerosis relapse prevention
Part of Brain & nervous system, Immune system & allergy clinical trials.
This study tests whether an mRNA vaccine (mRNA-1195) can help prevent relapses in people with early relapsing multiple sclerosis (MS). It compares the vaccine to a placebo (a shot with no active ingredient) to see if it is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- You have been diagnosed with relapsing multiple sclerosis (MS) within the last 2 years, including a first attack or a finding on MRI without symptoms.
- You have a positive test for Epstein-Barr virus (EBV), a common virus linked to MS.
- You have been neurologically stable for at least 30 days before starting the study.
- If you can become pregnant, you must not be pregnant or breastfeeding and must use reliable birth control.
- You have not taken strong immune-suppressing drugs (like high-dose steroids) in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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