Testing 9MW3011 for polycythemia vera in resistant patients
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a new drug called 9MW3011 for people with polycythemia vera (PV) who haven't done well on or can't take standard treatments like hydroxyurea or interferon. The goal is to see if the drug is safe and how it works in your body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You have a confirmed diagnosis of polycythemia vera (PV) using 2016 World Health Organization criteria.
- Your PV has not responded well to or you can't take standard treatments like hydroxyurea or interferon alpha.
- You must stop taking certain other PV medicines before the trial starts (this is called a 'washout' period).
- You cannot have an enlarged spleen, serious heart problems, uncontrolled high blood pressure, or active infections.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an injection called BEBT-507 for people with polycythemia vera (a blood condition that makes too many red blood cells). It's for those who haven't responded well to or can't tolerate standard treatments like hydroxyurea or interferon. The goal is to see if this new drug can help control the disease.
This Phase 3 study compares ruxolitinib against hydroxycarbamide or interferon as the first treatment for people with high-risk polycythemia vera. It aims to see which option works better to reduce disease-related problems and complications.
This Phase 2 trial tests a combination of pegylated interferon and ruxolitinib in adults with polycythemia vera who can’t tolerate hydroxyurea or don’t respond well to it. If you qualify, it may help control blood counts and disease symptoms when standard treatment hasn’t worked.
This trial tests an investigational drug called rusfertide for people with polycythemia vera whose red blood cell levels are not well controlled. It aims to see if rusfertide can help manage your condition without needing as many phlebotomies (blood removal procedures).
This trial tests an experimental pill called bomedemstat for people with polycythemia vera who have not responded well to or could not tolerate hydroxyurea. It aims to see if the drug can help control red blood cell counts with fewer side effects.
This study is testing a medicine called ropeginterferon alfa-2b for people with polycythemia vera (a blood condition) who do not have a swollen spleen that causes symptoms. It looks at how well the medicine works and how it affects your daily life through simple questionnaires.
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