Pimavanserin for impulse control problems in Parkinson's disease
Part of Brain & nervous system, Mental health clinical trials.
This trial tests if pimavanserin can reduce impulse control disorders like gambling, shopping, hypersexuality, or overeating in people with Parkinson's disease. It aims to help those whose symptoms are moderate but not too severe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Parkinson's disease for at least 1 year.
- You are between 35 and 75 years old.
- You have moderate impulse control problems (like gambling, shopping, hypersexuality, or overeating) that started after your Parkinson's diagnosis and after starting dopamine medications.
- You have been on a stable dose of your Parkinson's medications for at least 1 month and agree to stay on the same dose during the trial.
- You have not had deep brain stimulation in the past year, and your settings have been stable for at least 1 month.
- You do not have severe depression, suicidal thoughts, dementia, or certain heart or electrolyte problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a prediction model can help prevent drug-induced impulse control disorders (like compulsive gambling or shopping) in people with Parkinson's disease who are taking dopamine agonists. It aims to lower the risk of these side effects by adjusting treatment based on the model's predictions.
This study uses a special PET brain scan tracer to better understand serotonin receptor activity in people with certain neurodegenerative conditions, especially when they develop hallucinations or delusions. The results may help researchers improve how these brain changes are measured and tracked over time.
This trial tests whether a type of non-invasive brain stimulation called TMS can help reduce impulse control problems (like gambling or compulsive eating) that are caused by Parkinson's medications. It's for people with Parkinson's who are living with these side effects.
This trial tests whether deep brain stimulation (DBS) of the subthalamic nucleus can help control impulse control problems (like gambling, overeating, or shopping) in people with Parkinson's disease. It is for patients whose medication-related impulse symptoms are moderate to severe and who are good candidates for DBS surgery.
This study tests a new once-daily pill called BHV-8000 in people who were recently diagnosed with early Parkinson's disease and are not yet on medication. The goal is to see if it can slow the progression of symptoms and improve quality of life.
This study tests whether a medication called mirabegron, a behavioral program, or both can improve urinary symptoms (like urgency and leakage) in people with Parkinson's disease. It may help you have better bladder control and daily comfort.
Hear when a new Parkinson Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.