Clin2
NCT06498349Possibly a fitRecruiting

DBS for Parkinson's impulse control problems

Parkinson DiseaseImpulse Control Disorders

Part of Brain & nervous system, Mental health clinical trials.

This trial tests whether deep brain stimulation (DBS) of the subthalamic nucleus can help control impulse control problems (like gambling, overeating, or shopping) in people with Parkinson's disease. It is for patients whose medication-related impulse symptoms are moderate to severe and who are good candidates for DBS surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are 70 years old or younger.
  • You have had Parkinson's disease for at least 4 years.
  • You have a moderate to severe impulse control problem (like gambling, overeating, shopping, or compulsive medication use) related to your Parkinson's medication.
  • Your Parkinson's symptoms improve by at least 30% when you take your regular medication.
  • You do not have dementia or severe depression.
  • You are willing to have deep brain stimulation (DBS) surgery and have no medical reasons that would make it unsafe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06485986Recruiting
Brain Networks in Parkinson's and DBS

This study uses a brain scan called MEG to look at how Parkinson's disease and impulse control disorders affect brain networks in people who have already had deep brain stimulation (DBS) surgery. You will be asked to delay your morning medication so the researchers can study your brain without the effects of the drugs.

Oxford
NCT07022522Recruiting
Brain stimulation frequencies for impulse control in Parkinson's

This study tests whether stimulating specific parts of the brain's subthalamic nucleus at different frequencies can improve control over unwanted movements or impulses in people with Parkinson's disease. If you are planning to have DBS surgery, this trial may help find a better way to use the device.

Beijing, Beijing Municipality
NCT06008717Not yet recruiting
Deep brain stimulation for early Parkinson's disease

This trial tests whether deep brain stimulation (a surgical treatment that uses electrical pulses to calm overactive brain areas) can help people in the early stages of Parkinson's disease. If you join, you'll get either the stimulation or a placebo (inactive) treatment, and the study will see if it improves your symptoms.

NCT06618157Enrolling by invitation
Brain stimulation study for Parkinson's tremor

This study tests a new way to adjust deep brain stimulation (DBS) for Parkinson's disease. It focuses on people who still have at least mild tremor after their DBS device has been in place for three months or more, to see if targeting specific brain connections can help improve tremor control.

Durham, North Carolina
NCT06013956Recruiting· Phase 4
Personalized deep brain stimulation for Parkinson's

This study tests a personalized way to adjust deep brain stimulation (DBS) therapy in real time for people with Parkinson's disease. It aims to improve how DBS works by tailoring it to each person's needs.

Cleveland, Ohio
NCT07105280Not yet recruiting
Closed-loop stimulation for Parkinson's disease

This trial tests a new way to adjust deep brain stimulation (DBS) in real time, based on brain signals, to better control symptoms like speech problems, freezing, and motor fluctuations. It aims to improve daily life for people with Parkinson's who have had DBS for at least 6 months.

Amsterdam

Hear when a new Parkinson Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.