Comparing two sedatives to prevent delirium after heart surgery
Part of Brain & nervous system, Mental health clinical trials.
This trial tests whether a newer sedative (remimazolam) or a commonly used one (dexmedetomidine) is better at preventing delirium after planned heart surgery that requires a heart-lung machine. If you are having elective coronary bypass or valve surgery, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for elective heart surgery (bypass surgery or valve replacement).
- You do not have allergies to the study drugs (remimazolam or dexmedetomidine).
- You have no history of schizophrenia, epilepsy, severe dementia, or other serious brain conditions.
- You can communicate normally (no severe vision/hearing problems or language barriers).
- Your surgery is expected to last at least 2 hours on the heart-lung machine with at least 90 minutes of the aorta clamped.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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