Comparing two sedatives to prevent confusion after heart surgery
Part of Brain & nervous system, Mental health clinical trials.
This study compares two sedative medications (remimazolam and dexmedetomidine) to see which one better prevents confusion or disorientation (called delirium) after heart surgery. Participants receive one of the two medicines during their operation, and researchers monitor them for signs of delirium during recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must be scheduled for elective (non-emergency) heart surgery, such as bypass or valve surgery.
- You must not have a history of certain psychiatric or neurological conditions (like schizophrenia, epilepsy, or severe dementia).
- You must not have severe liver or kidney problems.
- You must not be allergic to the study drugs (remimazolam or dexmedetomidine).
- Your surgery must include a heart-lung machine with a bypass time of at least 2 hours and a clamping time of at least 90 minutes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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