Clin2
NCT06757335Possibly a fitNot yet recruiting

Oral hp568 for hormone receptor positive advanced breast cancer

Breast Cancer

Part of Cancer, Skin clinical trials.

This trial tests an oral pill (HP568) for people with a certain type of advanced breast cancer that has grown despite previous hormone therapy. The pill aims to block the cancer's growth signals and may help slow the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
204 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are a woman between 18 and 75 years old.
  • You have advanced breast cancer that is ER+ (hormone receptor positive) and HER2- (not HER2 positive) that has spread or cannot be removed by surgery.
  • You have had at least one previous hormone therapy for at least 6 months.
  • You have had no more than 2 chemotherapy treatments for your advanced disease.
  • Your cancer has shown growth or spread on imaging during or after your most recent treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06149130Recruiting· Phase 2
Testing adebrelimab, dalpiciclib, and hormone therapy for advanced breast cancer

This trial tests a combination of a new immunotherapy drug (adebrelimab) with a targeted pill (dalpiciclib) and standard hormone therapy for women with advanced hormone receptor positive, HER2 negative breast cancer. It may help patients who have not yet had certain prior treatments, aiming to slow the cancer's growth.

Wuhan, Hubei
NCT04563507Recruiting· Phase 2
Immunotherapy plus hormone therapy for metastatic ER-positive breast cancer

This Phase 2 study tests a combination of immune-based treatments along with hormone (endocrine) therapy to slow or shrink advanced, hormone-receptor positive, HER2-negative breast cancer. You may be a candidate if your cancer has progressed after standard hormone-blocking medicines and you can start treatment with CDK4/6 medicine plus an aromatase inhibitor.

New York, New York
NCT06650748Enrolling by invitation· Phase 2
A study of hormone therapy with or without a targeted drug for breast cancer

This trial tests if adding a targeted drug (CDK4/6 inhibitor) to hormone therapy works better than hormone therapy alone for women with a certain type of breast cancer (HR+/HER2-). The study measures the activity of tumor cells (Ki-67) to help decide treatment.

Beijing
NCT06805812Recruiting
Predicting outcomes of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer

This study looks at how well a type of targeted therapy (called CDK4/6 inhibitors) combined with hormone therapy works as the first treatment for advanced breast cancer that is hormone receptor-positive and HER2-negative. Researchers want to find patterns that could help predict which patients benefit most.

Aviano
NCT07019363Recruiting· Phase 3
CDK4/6 inhibitor plus hormone therapy for high-risk breast cancer

This trial tests whether adding a CDK4/6 inhibitor (a type of targeted pill) to standard hormone therapy after surgery can lower the risk of breast cancer coming back in women with high-risk, hormone-receptor-positive, HER2-positive early breast cancer.

Shanghai
NCT06515470Recruiting· Phase 1
Testing BTX-9341 for advanced breast cancer

This trial tests a new oral drug, BTX-9341, for people with advanced or metastatic hormone receptor-positive, HER2-negative breast cancer who have already had certain treatments, including a CDK4/6 inhibitor. The goal is to see if it is safe and effective.

Rochester, Minnesota

Hear when a new Breast cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.