Clin2
NCT06761183Possibly a fitRecruiting

Gene therapy for arm and leg weakness after stroke

Ischemic Stroke

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial tests a new gene therapy called NXL-001 for people who still have moderate to severe arm or leg weakness 2 to 12 months after a stroke. The treatment aims to help the brain repair itself and improve movement.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
9 people
Ages
40 years to 75 years
Study type
Interventional

Who can take part

  • You are between 40 and 75 years old.
  • You had a stroke 2 to 12 months ago that left you with moderate to severe weakness in an arm or leg.
  • Your stroke was in the part of the brain that controls movement, and it is a certain size (20-80 ml).
  • You have already tried standard rehabilitation therapy but still have significant weakness.
  • You are able to attend follow-up visits and undergo rehabilitation training.
  • You do not have certain other medical conditions, like epilepsy, recent bleeding in the brain, or active infections.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06612710Recruiting· Phase 1
A study of NouvSoma001 for recent stroke recovery

This trial tests a new treatment called NouvSoma001 for people who have had an ischemic stroke within the last week. It aims to see if the treatment is safe and helps improve muscle strength and overall recovery.

Wuhan, Hubei
NCT07841496Not yet recruiting· Phase 2
Study of a new drug for stroke recovery after a past stroke

This study tests an experimental drug called ALT001 for people who are still recovering from a stroke that happened at least 6 months ago and within the last 5 years. The drug may help improve limb weakness that persists after a stroke.

Beijing, Beijing Municipality
NCT07478822Recruiting· Phase 3
Botulinum toxin study for arm spasticity after stroke

This study tests a new botulinum toxin injection (YY001) for adults whose arm muscles are tight or stiff after a stroke. It looks at whether repeated treatments help with daily activities like washing and dressing.

Beijing
NCT06704347Not yet recruiting· Phase 1
Gene therapy for ALS symptoms

This study tests an experimental gene therapy called XT-150, which is given as an injection into the fluid around the spinal cord. The goal is to see if it is safe and to gather information that could help treat ALS muscle weakness.

Phoenix, Arizona
NCT06995625Recruiting· Phase 1
Stem cell particles for recent stroke recovery

This trial tests whether stem cell-derived extracellular vesicles can help people recover after a moderate to severe stroke. You may join if you had a stroke in the last 5 days and still have arm or leg weakness, even after standard treatments like clot-busting drugs or clot removal.

Suwon, Gyeonggi-do
NCT07627516Recruiting
Spinal cord stimulation for arm and leg weakness after stroke

This trial tests whether a spinal cord stimulation device—a small implant that sends gentle electrical signals to your spinal cord—can help improve arm and leg strength and movement in people who had a stroke at least 6 months ago and haven't fully recovered with regular therapy. The goal is to see if this treatment is safe and effective.

Hangzhou, Zhejiang

Hear when a new Ischemic Stroke trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.