CAR T-cell therapy for CD123+ blood cancers
Part of Blood & lymphatic, Cancer, Immune system & allergy, Skin clinical trials.
This trial tests a new type of immunotherapy called CAR T-cells that target a protein called CD123 on cancer cells. It is for people with certain blood cancers (AML, MDS-IB2, BPDCN, or ALL) that have come back or not responded to other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a blood cancer (AML, MDS-IB2, BPDCN, or ALL) that is CD123-positive.
- Your cancer has come back or didn't respond well to at least 2 rounds of chemotherapy or other standard treatments.
- You are between 18 and 70 years old.
- You have a stem cell donor who is a match and has been cleared for use.
- You are not pregnant and agree to use effective birth control if you or your partner could have children.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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