Clin2
NCT06773312Possibly a fitRecruiting

Study of BC001 plus Sintilimab and XELOX for advanced stomach cancer

Advanced or Metastatic Gastric CancerGastroesophageal Junction Adenocarcinoma

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of three drugs (BC001, Sintilimab, and XELOX chemotherapy) for people with advanced or metastatic HER-2 negative stomach cancer or cancer where the stomach meets the esophagus. The goal is to see if this combination works better than standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
80 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have HER-2 negative advanced or metastatic stomach or gastroesophageal junction cancer that hasn't been treated with systemic therapy before (or you finished prior treatment more than 6 months ago).
  • You must have at least one measurable tumor seen on a CT or MRI scan.
  • You must be able to eat and drink normally.
  • Your overall health status (ECOG score) must be 0 or 1, meaning you are fully active or only have minor limitations.
  • You must have adequate kidney, liver, and blood cell function, with specific lab test results.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06196697Recruiting· Phase 2
New immunotherapy combo for advanced stomach cancer

This clinical trial is testing a combination of two immunotherapy drugs (AK104 and AK112) plus chemotherapy as the first treatment for advanced stomach or gastroesophageal junction cancer. It aims to see if this combination helps control the cancer better than standard therapy.

Harbin
NCT07621484Not yet recruiting· Phase 2
Heated chemotherapy plus immunotherapy and standard chemo for stomach cancer

This trial tests a new approach for locally advanced stomach cancer. It uses a heated chemotherapy bath (HIPEC) before giving a combination of two chemotherapy drugs (SOX or XELOX) plus an immunotherapy drug called serplulimab. This aims to shrink the tumor and improve the chances of successful surgery and long-term control.

NCT07859410Not yet recruiting
Immunotherapy plus chemoradiation before surgery for stomach cancer

This trial tests whether adding an immunotherapy drug called sintilimab to chemotherapy and radiation before surgery can help shrink tumors and improve outcomes for people with gastroesophageal junction cancer. It is designed for patients who have not had previous treatment for this cancer.

Hefei, Anhui
NCT06023758Recruiting· Phase 2
Study of two drugs with or without chemo for HER2-positive stomach cancer

This study tests two new immunotherapy drugs (KN026 and KN046) with or without chemotherapy (XELOX) for people with a specific type of advanced stomach cancer that makes too much HER2 protein. The goal is to see if this combination can shrink tumors or slow the cancer.

Beijing, Beijing Municipality
NCT06506292Recruiting· Phase 2
Study of adebrelimab plus chemo before and after stomach cancer surgery

This trial tests combining adebrelimab (an immunotherapy) with chemotherapy (XELOX) before and after surgery for stomach cancer that hasn't spread. The goal is to see if this approach helps shrink tumors and improves outcomes.

Tianjin, Tianjin Municipality
NCT05918094Recruiting· Phase 3
Testing new chemo plan plus immunotherapy for stomach cancer

This phase 3 study compares two versions of a first-time treatment for HER2-negative advanced stomach or gastroesophageal cancer, both including immunotherapy (sintilimab). It looks for a safer or more effective way to slow cancer growth or improve outcomes.

Guangzhou, Guangdong

Hear when a new Gastroesophageal Junction Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.