Surgery for failed root canal in front teeth
Treatments studied
Part of Mouth & dental, Women’s health & pregnancy clinical trials.
This trial tests a surgical procedure to treat front or premolar teeth where a previous root canal has failed and there is an infection at the root tip. The surgery aims to remove the infection and save the tooth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- The problem tooth must be a front tooth or a premolar (the teeth just behind the canines) in the upper or lower jaw.
- You must have had a root canal that didn't work, and an X-ray showing a small infection or cyst at the tip of the root.
- The tooth must not be cracked vertically down the root (a vertical root fracture).
- The tooth must be restorable (can still be fixed with a filling or crown) and not so loose it moves easily.
- You must be able to have surgery safely — this means not pregnant, not a smoker, and free of serious health problems that would make surgery risky.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether using a special platelet-rich concentrate (i-PRF) during a root canal retreatment can help heal infection at the tip of the root better than standard retreatment alone. It is for adults with a previously treated upper front tooth that now shows signs of infection on X-ray.
This study tests whether adding a concentrated blood clot (L-PRF) to standard root-end surgery helps tooth-related infections heal faster and better. You may be a good fit if you have a persistent infection at the tip of a tooth root and need this type of surgery.
This trial compares different medicines placed inside the tooth after a failed root canal to help heal the infection at the root tip. If you have a back tooth that still has an infection even though it had a root canal years ago, this study may test which medicine works best for you.
This study tests whether using a special blood-derived gel (platelet-rich fibrin) inside the root canal can help heal infected mature teeth and avoid more serious procedures. It may be a good option for people with a single-rooted tooth that has a dead nerve and possibly an infection.
This trial tests whether using a bone graft (allograft) together with your own blood concentrate (iPRF) and a collagen membrane helps heal the bone and gum around a tooth with a long-standing infection. It might be a good option if you have a tooth that keeps getting infected despite a root canal and has a deep pocket on the cheek side.
This trial tests whether an injectable healing material called platelet-rich fibrin can help cover exposed tooth root in front teeth with gum recession. If it works, it may reduce tooth sensitivity and improve appearance for people with suitable, healthy teeth and gums.
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