Platelet-rich fibrin for saving infected mature teeth
Part of Infections, Mouth & dental clinical trials.
This study tests whether using a special blood-derived gel (platelet-rich fibrin) inside the root canal can help heal infected mature teeth and avoid more serious procedures. It may be a good option for people with a single-rooted tooth that has a dead nerve and possibly an infection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a single-rooted tooth (like a front tooth or a premolar) with a dead nerve, meaning it doesn't respond to cold or electric tests.
- The tooth may have a periapical infection (an infection at the root tip), which could cause pain, swelling, or an abscess, but it's okay.
- Your tooth must have a fully developed root (not a child's tooth) and no cracks, fractures, or signs of root resorption.
- Your tooth cannot have had a previous root canal treatment.
- You cannot be pregnant and must not have diabetes, HIV, or other conditions that weaken your immune system.
- Your tooth cannot be severely damaged needing extraction or a post, and the root canal must not be blocked or overly curved.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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