Using platelet-rich fibrin to heal dead teeth in adults
Part of Infections, Mouth & dental clinical trials.
This study tests whether using a special blood clot (platelet-rich fibrin) inside the root canal can help heal a dead tooth with or without an infection. It may be an option for adults with a mature single-rooted tooth that hasn't been treated before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a single-rooted tooth that is dead (the nerve is not alive) and may have an infection around the tip of the root.
- The tooth must be fully grown (root tip closed) and not cracked, broken, or resorbed.
- You have not had a root canal on this tooth before, and it is not planned for extraction or a post/crown.
- You are not pregnant and do not have diabetes, HIV, or a weakened immune system.
- The tooth's root canal is not too curved (less than 25 degrees) and not calcified (hardened).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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