Aromatase inhibitor effects on heart and brain health in breast cancer
Part of Brain & nervous system, Cancer, Heart & circulation, Hormones & metabolism clinical trials.
This study looks at how aromatase inhibitors (a type of hormone therapy for breast cancer) affect your heart and brain health over time. It compares women with breast cancer who have taken these drugs to healthy women of similar age.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman who has gone through menopause naturally (no surgery to remove ovaries) at least 1 year ago.
- You have had stage I, II, or III breast cancer that is hormone receptor positive and HER2 negative.
- You have been on an aromatase inhibitor for at least 2 years (if about 5–10 years since diagnosis) or are starting it soon (about 1 year after diagnosis).
- You have not taken tamoxifen before menopause.
- You do not have major heart disease, diabetes, kidney disease, or any condition that would make exercise testing unsafe.
- You can walk without a walker or wheelchair, are not extremely claustrophobic, and can understand English.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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