Clin2
NCT06791369Worth exploringNot yet recruiting

RYR1-related disease study

Neuromuscular DiseaseMalignant HyperthermiaCongenital MyopathyMultiminicore DiseaseNemaline MyopathyCentronuclear MyopathyCentral Core DiseaseCongenital Fiber Type Disproportion

Part of Bones, joints & muscles, Brain & nervous system, Genetic & congenital clinical trials.

This study looks at people with RYR1-related conditions like muscle weakness or malignant hyperthermia. The goal is to learn more about these conditions and how common they are.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
2,000 people
Ages
Any age
Study type
Observational

Who can take part

  • You have a known RYR1 gene mutation that causes disease.
  • You have symptoms of a related condition, such as a congenital myopathy or malignant hyperthermia.
  • You have been seen by a specialist at one of the national centers for this condition.
  • You live in one of the countries taking part in the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT00272883Recruiting
Study genes in congenital muscle weakness

This research study looks at genes and molecules to better understand congenital myopathies (birth-related muscle weakness). It may help explain the cause of symptoms and improve future diagnoses for you and your family.

Boston, Massachusetts
NCT06157268Recruiting
Study of muscle tiredness in congenital myopathies

This study follows patients with congenital myopathies to understand how their muscles get tired over time. It may help develop better treatments.

Nijmegen, Gelderland
NCT04064307Recruiting
Register people with myotubular or centronuclear myopathy

This study sets up a patient registry for people diagnosed with myotubular myopathy or centronuclear myopathy. Your information can help researchers better understand these conditions and plan future studies or treatments.

Newcastle upon Tyne, Tyne and Wear
NCT06833489Recruiting
Using genetic testing to find answers for rare muscle diseases

This study looks at leftover muscle tissue from people who have had genetic testing for rare muscle diseases but didn't get a clear diagnosis. The goal is to use newer genetic analysis to find the cause of their disease.

Marseille
NCT06287762Recruiting
Natural history study of RYR1-related disorders

This study follows people with RYR1-related disorders over time to learn how the condition progresses. It may help researchers plan future treatments.

Bethesda, Maryland
NCT06508164Recruiting
International registry for rare RYR2 variants

This study creates a registry for people with rare changes in the RYR2 gene that affect heart function. Researchers will collect information to better understand these conditions and improve care.

San Francisco, California

Hear when a new Congenital Myopathies trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.