Clin2
NCT06792435Possibly a fitActive, not recruiting

Study of XNW27011 for advanced solid tumors that failed standard therapy

Pancreatic Adenocarcinoma MetastaticLung Cancer (NSCLC)Ovarian CancerColorectal Cancer MetastaticBiliary Tract CancerGastric CarcinomaGastroesophageal Junction Adenocarcinoma

Part of Cancer, Digestive system, Hormones & metabolism, Lungs & breathing, Women’s health & pregnancy clinical trials.

This trial tests an investigational drug called XNW27011 for people with advanced solid tumors that have not responded to standard therapies. It may be especially relevant for tumors that have a specific protein called CLDN18.2, but it is not required for the first part of the study.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
240 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have an advanced solid tumor (like stomach, pancreatic, ovarian, lung, colorectal, or bile duct cancer) that has stopped responding to standard treatments or you cannot take them.
  • You are able to do daily activities with little help (ECOG score 0-2).
  • Your major organs (blood cells, liver, kidneys, heart) are working well enough, based on blood tests and heart tests.
  • If you have had treatments before, enough time has passed since your last dose (at least a few weeks, depending on the type).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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