Sildenafil to prevent memory problems from breast cancer treatment
Treatments studied
Part of Cancer clinical trials.
This study tests if sildenafil (a blood pressure medicine) can help prevent memory and thinking problems that some women with breast cancer may experience. It might help protect your brain during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 30 and 50 years old.
- You have had a period in the last 12 months.
- You have been diagnosed with ER+/HER2- breast cancer.
- You have not had chemotherapy before.
- You do not have untreated thyroid problems or diabetes, and you are not taking metformin.
- You do not have a history of memory problems or certain nerve or blood vessel diseases.
- You are not on certain medicines (like nitrates, alpha blockers, or PDE5 inhibitors).
- You are able to have an MRI (no metal implants, not severely claustrophobic).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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