Radiofrequency ablation for slow-flow vascular malformations
Part of Blood & lymphatic, Genetic & congenital, Heart & circulation clinical trials.
This trial tests using radiofrequency ablation (a treatment that uses heat to destroy abnormal tissue) instead of standard sclerotherapy (injection of a solution) for slow-flow vascular malformations. It aims to reduce symptoms like pain and swelling with a potentially less invasive approach.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Patient is older than 3 years.
- Diagnosis of a slow-flow vascular malformation (like lymphatic or venous malformation) confirmed by imaging (ultrasound or MRI).
- Malformation causes symptoms such as pain, swelling, limited use, or cosmetic concern, and the patient or guardian wants treatment.
- The malformation can be seen clearly enough on ultrasound to be safely targeted with the treatment.
- The malformation is located at least 3 mm below the skin and at least 3 mm away from critical nerves and blood vessels.
- Patient is able to undergo general anesthesia (and is not pregnant, if applicable).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two targeted medicines for people with certain types of vascular malformations (abnormal blood vessels). If you have a slow-flow malformation, you may receive alpelisib; if you have a fast-flow malformation, you may receive mirdametinib. Genetic testing is needed to see if your malformation has a specific change that these drugs target.
This study tests a treatment that uses microwave energy to shrink painful or troublesome abnormal blood vessels (vascular malformations). It may help reduce symptoms like pain and swelling without open surgery.
This trial tests a treatment called bleomycin electrosclerotherapy for people with slow-flow vascular malformations (abnormal blood vessels that do not flow quickly). The goal is to see if this treatment works well and is safe for these conditions.
This study is testing a treatment called electrosclerotherapy for low-flow venous malformations. It uses a medicine (bleomycin) injected into the abnormal blood vessels to shrink them. The goal is to see how well it works and how safe it is.
This study tests a treatment called bleomycin electrosclerotherapy (BEST) for people with low-flow vascular malformations—abnormal clusters of blood or lymph vessels that can cause pain or swelling. The treatment combines a drug (bleomycin) with a small electrical current to shrink these abnormal vessels, and the goal is to see if it helps when other treatments haven't worked well or the problem came back.
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
Hear when a new Vascular Anomalies trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.