Bleomycin electrosclerotherapy for stubborn vascular malformations
Treatments studied
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial tests a treatment called bleomycin electrosclerotherapy (BEST) for low-flow vascular malformations—abnormal blood vessel or lymph vessel growths that haven't responded well to previous treatments. The treatment involves injecting bleomycin (a medication) directly into the malformation and using electrical current to help destroy it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a low-flow vascular malformation (venous, lymphatic, capillary, or mixed) that either didn't respond to previous treatment or has come back
- Your lesion is no larger than 25 cm (about 10 inches) in its longest part
- You have no history of heavy bleomycin exposure (more than 100,000 IU total)
- You are not pregnant, breastfeeding, or a woman/man of childbearing age without reliable contraception
- You have healthy lung function and no acute lung infections or history of bleomycin-related lung damage
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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