Bleomycin with electrical current for low-flow vascular malformations
Treatments studied
Part of Genetic & congenital, Heart & circulation clinical trials.
This study tests a treatment called bleomycin electrosclerotherapy (BEST) for people with low-flow vascular malformations—abnormal clusters of blood or lymph vessels that can cause pain or swelling. The treatment combines a drug (bleomycin) with a small electrical current to shrink these abnormal vessels, and the goal is to see if it helps when other treatments haven't worked well or the problem came back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You have a low-flow vascular malformation (abnormal blood vessels like veins, lymph channels, capillaries, or a mix) that either did not improve after previous treatment or came back.
- The longest side of the treated area must be less than 25 cm (about 10 inches).
- If you are able to become pregnant or father a child, you must agree to use reliable birth control during the study.
- You must not have had certain lung problems, a known allergy to bleomycin, or have taken bleomycin before at a high total dose.
- You must not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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