Clin2
NCT06805552Possibly a fitRecruiting

Sarcopenia and targeted therapy in liver cancer

HCC - Hepatocellular Carcinoma

Part of Brain & nervous system, Cancer, Digestive system clinical trials.

This study looks at muscle loss in people with liver cancer who are receiving targeted therapy (TKIs). It aims to understand how muscle health affects treatment outcomes. You may qualify if you have intermediate or advanced liver cancer or earlier stage that hasn't responded to prior treatments.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
270 people
Ages
18 years and older
Study type
Observational

Who can take part

  • 18 years or older
  • Diagnosed with hepatocellular carcinoma (a type of liver cancer) by biopsy or imaging
  • Liver cancer is at an intermediate, advanced, or early stage that hasn't responded to prior local treatments
  • Starting or already on a type of targeted therapy called a TKI
  • Had a CT scan within the last 8 weeks before starting TKI therapy
  • Agree to participate and sign a consent form

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06156774Recruiting
Sarcopenia and frailty in lymphoma patients getting CAR-T therapy

This trial looks at how muscle loss (sarcopenia) and overall health affect outcomes in people with B-cell lymphoma who are receiving CAR-T cell therapy. It may help doctors better support patients before and after treatment.

Alessandria
NCT06736249Recruiting
Testing a new treatment for muscle loss in sarcopenia

This trial tests a new approach to treat sarcopenia (age-related muscle loss) by targeting a protein called HIF-1α. It compares older adults with sarcopenia to younger adults without it, all of whom are having hip or knee surgery.

Milan, Europe
NCT06475118Recruiting
Blood tests and scans to measure muscle loss in liver cancer

This study looks at whether measuring certain proteins in your blood (myokines) can help detect muscle loss (sarcopenia) in people with liver cancer, and compares these blood tests to special CT scans. If you're newly diagnosed with liver cancer and have a CT scan already, you may be able to join.

Reims
NCT05502198Recruiting
How muscle loss matters in advanced liver disease

This study looks at how loss of muscle strength or mass (sarcopenia) relates to advanced liver disease. It may help doctors understand which patients are at higher risk and could guide future care choices.

Eksjö
NCT07328009Recruiting· Phase 2
Personalized liver cancer treatment trial

This trial tests new treatment plans for people with advanced liver cancer that has worsened after initial therapy. The goal is to find more effective, personalized options based on how your cancer responds.

Shanghai, Shanghai Municipality
NCT07786792Not yet recruiting
Targeted therapy and immunotherapy for advanced liver cancer

This study is testing whether combining targeted therapy with immunotherapy (or using two immunotherapies together) can help people with liver cancer that cannot be surgically removed. The goal is to understand how well these treatments work and how they affect biomarkers (signals in your body that show treatment response).

Hear when a new HCC - Hepatocellular Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.