Mactientan for chest pain from small heart artery problems
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if mactientan, a blood vessel relaxer, can improve chest pain in people with coronary microvascular angina—where small heart arteries don't work right even though larger ones are clear. It aims to help those with ongoing angina symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have typical chest pain (angina).
- Your main heart arteries are not blocked (narrowing less than 50% or a normal flow reserve test).
- Tests show your small heart arteries are not working well (low flow reserve or high resistance).
- You are not pregnant or breastfeeding.
- You have not had a heart attack in the last 3 months.
- You do not have severe heart, kidney, liver, or blood problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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