tACS for hard‑to‑treat depression with inflammation
Part of Mental health clinical trials.
This study tests a non‑invasive brain stimulation method called tACS (transcranial alternating current stimulation) for people with difficult‑to‑treat depression and signs of inflammation. It aims to see if this treatment can help when standard medications haven't worked well enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- You have been diagnosed with depression by a psychiatrist.
- Your depression symptoms are moderately severe (score of 17 or more on a standard depression scale).
- You have a blood test showing a certain level of inflammation (CRP between 0.85 and 10 mg/L).
- You have tried at least two different depression treatments that didn't work well (DM-TRD score of 12.5 or higher).
- You have been on the same antidepressants or antipsychotics for at least 2 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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