Comparing two immunotherapy drugs for advanced head and neck cancer
Treatments studied
Part of Cancer clinical trials.
This trial compares two immunotherapy drugs (ivonescimab and pembrolizumab) given with standard chemotherapy before and possibly after surgery for advanced head and neck cancer that can be removed. The aim is to see which drug is better at shrinking the tumor and improving outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have head and neck cancer (in the mouth, throat, voice box, or lower throat) that can be removed with surgery.
- Your cancer is at a locally advanced stage (stage III or IVB), but not involving certain critical areas.
- You have at least one tumor that can be measured on scans.
- You are in good overall health (able to care for yourself and be up and about).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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