Preventing infantile spasms from coming back
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests whether a longer course of steroids can keep infantile spasms from returning in babies who have already responded to standard treatment. It may help reduce the chance of relapse.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is between 2 and 18 months old.
- Your baby has been diagnosed with infantile spasms and treatment (like prednisolone, ACTH, or vigabatrin) stopped their spasms, confirmed by an EEG.
- Your baby does not have serious high blood pressure, an active infection, or other conditions that would make extended steroid use risky.
- Your baby has not used any artisanal cannabis product in the last 14 days.
- Your baby is not currently on the ketogenic diet.
- Your baby does not have a vagal nerve stimulator that was implanted or adjusted recently, and has not had epilepsy surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies brain electrical activity in children with West syndrome (infantile spasms) using a safe, non-invasive magnetic stimulation technique. It tests how the brain responds before and after starting ACTH or a ketogenic diet, which are standard treatments for infantile spasms.
This trial tests whether adding a high-dose steroid (prednisolone) to vigabatrin works better than vigabatrin alone for infants with infantile spasms. It may help reduce seizures and improve early development, but your child’s prior treatments and health conditions must fit the study rules.
This study follows children and teens with rare forms of epilepsy to better understand their condition over time in real-life care. It may help doctors improve future care plans and support for families.
This Phase 2 trial studies fenfluramine to treat infantile spasms that haven’t improved after standard medicines (ACTH and vigabatrin). If you/your child has ongoing seizures, the study may offer another treatment option and will monitor safety closely, especially heart-related side effects.
This trial compares two types of brain stimulation—deep brain stimulation (DBS) and vagus nerve stimulation (VNS)—to see which works better for epileptic spasms in children with drug-resistant epilepsy. If your child has not responded to two or more seizure medicines, this study might help find a new way to control their spasms.
This trial tests whether starting a special high-fat diet (ketogenic diet) early can prevent epileptic spasms in babies with genetic epilepsy. It uses a specific formula called KetoVie and is for infants under 9 months old.
Hear when a new West Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.