Cryoprobe Biopsy for Chronic Rejection in Lung Transplant
Part of Lungs & breathing clinical trials.
This trial tests a new biopsy method called cryoprobe (using a cold probe) to better detect chronic rejection in lung transplant patients. It is for patients who already need a lung biopsy, either for routine monitoring or because of a concern.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have received a double lung transplant (not a single lung)
- You are already scheduled for a lung biopsy as part of your care
- You are not taking blood thinners that cannot be stopped before the procedure (aspirin is fine)
- You do not have a bleeding disorder or very low platelets
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study uses a special MRI scan (called hyperpolarized gas MRI) to check for signs of lung rejection after a transplant. The goal is to see if the MRI can help detect rejection earlier and more safely than standard bronchoscopy alone.
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This study looks for lab “clues” that can help predict how well someone’s lungs will do after a lung transplant. It may help doctors spot transplant-related problems earlier so care can be planned sooner.
This study tests a new method called 'cryobiopsy' (a cold biopsy) to take samples from lung spots. The goal is to see if it works well and is safe in everyday practice.
This study tests a new freezing tool (cryoprobe) used during lung transplant surgery to see if it can safely destroy abnormal tissue. The procedure is done on the lungs after they are removed from the body, so it does not affect the patient directly.
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