Clinical trials
Lung Transplant Rejection clinical trials
Below are recruiting lung transplant rejection clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06948097RecruitingPhase 1
Testing fostamatinib for lung transplant patients with new donor-specific antibodies
This trial tests a drug called fostamatinib to see if it is safe and tolerable for lung transplant patients who develop new antibodies against their donor lung. It aims to prevent rejection without harming the new lung.
Stanford, CaliforniaAges 18–99 - NCT06476132RecruitingPhase 2
Belumosudil for lung transplant patients at risk of chronic rejection
This trial tests whether the drug Belumosudil can help prevent chronic lung rejection in people who recently had a lung transplant and showed signs of early rejection. It may improve long-term lung health.
Los Angeles, CaliforniaAges 12 years+ - NCT05586906Recruiting
Breath test to detect lung transplant problems early
This trial looks at a simple, noninvasive breath test to spot early lung transplant dysfunction after a lung transplant. Because it focuses on testing after the transplant, it may help your care team catch issues earlier.
ZurichAges 18 years+ - NCT04837339Recruiting
Testing markers to predict problems after lung transplant
This study looks for lab “clues” that can help predict how well someone’s lungs will do after a lung transplant. It may help doctors spot transplant-related problems earlier so care can be planned sooner.
SuresnesAges 15 years+ - NCT04582279Recruiting
Lung ultrasound test to rule out rejection after lung transplant
This study checks whether a painless lung ultrasound can help tell when rejection is unlikely after a lung transplant. If it works, it could reduce the need for other tests in people who feel well.
Jacksonville, FloridaAges 18 years+ - NCT02812290Recruiting
Microarray testing during lung transplant biopsy
This study looks at using a special lab test (microarrays) on tissue taken during a lung transplant biopsy. It aims to learn how the test may help doctors better diagnose and guide care after transplant.
Phoenix, ArizonaAges 18 years+ - NCT06082037RecruitingPhase 3
Testing belumosudil for chronic lung allograft dysfunction after transplant
This trial tests an oral medication called belumosudil for people with chronic lung allograft dysfunction (CLAD) after a double lung transplant. It may help slow the decline in lung function.
Birmingham, AlabamaAges 18 years+ - NCT07046910RecruitingPhase 2
MRI to detect lung rejection after transplant
This study uses a special MRI scan (called hyperpolarized gas MRI) to check for signs of lung rejection after a transplant. The goal is to see if the MRI can help detect rejection earlier and more safely than standard bronchoscopy alone.
Charlottesville, VirginiaAges 18–80 - NCT07516379Recruiting
Understanding Lung Rejection After Transplant
This study follows people with serious lung disease before and after lung transplant to understand how rejection happens and what warning signs to watch for. By studying your blood, tissue samples, and imaging, researchers hope to better predict and prevent transplant rejection.
Bethesda, MarylandAges 18–75 - NCT06514378RecruitingPhase 1
Safety of stem cells for chronic lung transplant rejection
This trial tests whether a single dose of stem cells given through a bronchoscope is safe for people whose lungs are failing after a transplant. It may help those with a condition called bronchiolitis obliterans syndrome (BOS), a type of chronic rejection that makes it harder to breathe.
MadridAges 18 years+ - NCT06824402Recruiting
Cryoprobe Biopsy for Chronic Rejection in Lung Transplant
This trial tests a new biopsy method called cryoprobe (using a cold probe) to better detect chronic rejection in lung transplant patients. It is for patients who already need a lung biopsy, either for routine monitoring or because of a concern.
Rochester, MinnesotaAges 18–99 - NCT06679257Recruiting
Liquid biopsy for lung transplant damage classification
This study tests a simple blood test (liquid biopsy) to detect and classify damage to a transplanted lung. It aims to find signs of rejection or injury earlier, which could help doctors treat problems sooner.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT06990711RecruitingPhase 1
Siltuximab for antibody-mediated rejection after lung transplant
This trial tests a drug called siltuximab to see if it can help treat a type of lung rejection called antibody-mediated rejection (AMR) in people who have had a lung transplant. You may be eligible if you are currently hospitalized for AMR and are already planning to receive standard treatments.
St Louis, MissouriAges 18 years+ - NCT06112951Recruiting
ECP treatment for early signs of lung transplant rejection
This trial tests whether a therapy called extracorporeal photopheresis (ECP) can stop early, silent rejection in lung transplant patients. It is for people who have developed donor-specific antibodies but still have normal lung function.
ViennaAges 18 years+ - NCT07434869Recruiting
Blood and image markers for ECP response in lung transplant CLAD
This study looks at whether blood tests and MRI scans can predict how well ECP (a blood-filtering treatment) works for people with CLAD after a lung transplant. If you’ve been prescribed ECP for CLAD and haven’t had it before, you may be able to help researchers find better ways to tailor treatment.
Boston, MassachusettsAges 7 years+ - NCT05375149Recruiting
Breath particle study after lung transplant
This study looks at tiny particles in exhaled breath after a lung transplant. It may help researchers understand how the lungs are doing after transplant by using breath samples.
Lund, Skåne CountyAges 16–75 - NCT06399302Recruiting
Improving outcomes for lung transplant patients
This study looks at ways to improve outcomes for people who are waiting for or have recently received a lung transplant. It aims to find better management strategies for both donors and recipients.
Los Angeles, CaliforniaAges 18 years+ - NCT07035743Recruiting
Lung response to exercise after double lung transplant
This study looks at how your lungs respond to exercise after a double lung transplant. It aims to understand normal recovery patterns and may help improve care for other transplant recipients.
TaoyuanAges 20 years+ - NCT06018766RecruitingPhase 2
LAM-001 for lung transplant patients with BOS
This study tests whether the drug LAM-001 can help people who have developed a condition called bronchiolitis obliterans syndrome (BOS) after a double lung transplant. BOS causes a slow decline in lung function, and this trial aims to see if LAM-001 can slow or stop that decline.
San Francisco, CaliforniaAges 18 years+ - NCT06538376Recruiting
New portable chest X-ray for ICU patients
This study tests a new portable chest X-ray that can be used in the ICU to check for problems like fluid in the lungs, trouble breathing, or swallowing issues. It is designed to help doctors see these problems more easily without moving you to the radiology department.
Boston, MassachusettsAges 18 years+ - NCT04787822Enrolling by invitation
Follow-up for people in a lung transplant research group
This study checks long-term health and well-being in people who previously joined a lung transplant research study. It may help doctors understand long-term changes after transplant and improve future care.
Birmingham, AlabamaAges 13 years+ - NCT07243964Recruiting
Predicting lung transplant outcomes with molecular analysis
This study uses advanced blood and tissue testing to predict how well a new lung will work after transplant. If you've had a lung transplant and are stable, you may help researchers improve care for future patients.
ShanghaiAges 18 years+ - NCT06997471RecruitingPhase 1
Safety of modified stem cell infusion with organ transplant
This early-phase trial tests whether it is safe to give a special type of stem cell transplant (with the naïve T cells removed and only memory T cells left) to people receiving organ transplants. It is for children getting intestine or lung transplants, and for children or adults getting kidney transplants.
Madrid, MadridAges birth+ - NCT06918990RecruitingPhase 1
CarBel for antibody-mediated rejection after kidney transplant
This study tests a new drug called CarBel to treat antibody-mediated rejection in kidney transplant patients. The goal is to see if it can help stop the rejection and protect your new kidney.
Birmingham, AlabamaAges 18–75
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Lung Transplant Rejection trials by city
Studies with a site in or near these metro areas.
Lung Transplant Rejection trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for lung transplant rejection?
- Yes. Clin2 currently lists 29 recruiting lung transplant rejection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung transplant rejection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung transplant rejection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.