Stem cell therapy for liver failure after transplant
Part of Digestive system clinical trials.
This trial tests if a therapy made from stem cells (called MSC-EVs) can help patients recover from severe liver failure after a liver transplant. It is for people who had a sudden worsening of chronic liver disease and needed a new liver.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old
- You had a liver transplant because of acute-on-chronic liver failure (a sudden severe worsening of long-term liver disease)
- You are willing to give consent to join the study
- You do not have a past or current cancer
- You do not have an active infection that is not well controlled
- You are not HIV positive or have active hepatitis C
- This is your first liver transplant (not a retransplant)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether adding mesenchymal stem cells to a blood-cleaning procedure helps people with acute liver failure recover. It may reduce inflammation and improve liver function.
This trial looks at how well stem cell (MSC) treatment works for people with severe liver failure caused by hepatitis B. It checks what factors affect the success of the treatment.
This trial tests whether infusing stem cells (from a healthy donor) can help people with sudden liver failure that is not getting better with standard medicines and is not caused by viruses. It aims to improve liver function and possibly avoid the need for a transplant.
This trial tests whether injecting special stem cells (called mesenchymal stem cells) can help people with a sudden worsening of chronic liver disease (called acute-on-chronic liver failure) who do not have a virus as the cause. It is for patients who are too sick for standard treatment but who cannot get a liver transplant right away.
This trial tests whether stem cells from donated umbilical cords can help people with acute-on-chronic liver failure, a sudden worsening of chronic liver disease. The goal is to see if this treatment improves liver function and survival.
This early-phase study tests whether stem cells (called mesenchymal stem cells) are safe and can help people with a sudden, severe liver failure. You may qualify if your liver is failing quickly and you are not eligible for a transplant.
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