Cell-free therapy for people with liver failure after liver transplant
Part of Digestive system clinical trials.
This trial tests whether a special cell-free therapy (called MSC-EVs) can help people recover after a liver transplant for acute-on-chronic liver failure. It uses tiny particles from stem cells that may reduce inflammation and improve liver function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have a condition called acute-on-chronic liver failure, which is a sudden severe worsening of a long-term liver problem.
- You are having (or have just had) a liver transplant because of this liver failure.
- You must agree to the trial after understanding its purpose and methods.
- You have not had cancer in the past, do not have an active uncontrolled infection, and are not HIV or hepatitis C positive.
- You have not had a previous liver transplant and are not having a multi-organ transplant (like a kidney with the liver).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding mesenchymal stem cells to a blood-cleaning procedure helps people with acute liver failure recover. It may reduce inflammation and improve liver function.
This trial looks at how well stem cell (MSC) treatment works for people with severe liver failure caused by hepatitis B. It checks what factors affect the success of the treatment.
This study tests whether a special type of stem cell therapy (called mesenchymal stem cells) can help people with a severe liver condition called acute-on-chronic liver failure (ACLF). The goal is to see if this treatment can improve liver function and reduce the need for a liver transplant.
This trial tests whether stem cells from donated umbilical cords can help people with acute-on-chronic liver failure, a sudden worsening of chronic liver disease. The goal is to see if this treatment improves liver function and survival.
This trial tests whether a special type of stem cell therapy can help people with severe liver failure (called ACLF) that is not caused by a virus. The treatment may help your liver recover and improve your overall condition.
This study tests a new treatment using stem cells for people with liver cirrhosis caused by alcohol, hepatitis B, or hepatitis C. The goal is to see if it is safe and if it can help improve liver function.
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