Stem cell therapy for severe liver failure (Phase 1 safety study)
Treatments studied
Part of Digestive system clinical trials.
This early-phase study tests whether stem cells (called mesenchymal stem cells) are safe and can help people with a sudden, severe liver failure. You may qualify if your liver is failing quickly and you are not eligible for a transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a severe, sudden worsening of long-term liver disease (called acute-on-chronic liver failure) that is not caused by a virus.
- Your liver failure must be at a certain severity level (MELD score above 18 or AARC grade 2 or higher) and you should not be able to get a liver transplant.
- You must be between 18 and 65 years old.
- You cannot have an active infection, bleeding, or cancer (including liver cancer beyond certain limits).
- You cannot have other serious conditions like heart disease, kidney disease, or be on immune-suppressing medicines.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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