Stem cell therapy for severe liver failure
Treatments studied
Part of Digestive system clinical trials.
This study tests whether a special type of stem cell therapy (called mesenchymal stem cells) can help people with a severe liver condition called acute-on-chronic liver failure (ACLF). The goal is to see if this treatment can improve liver function and reduce the need for a liver transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a type of severe liver failure called ACLF that is not caused by a viral infection (like hepatitis B or C).
- You have no current severe infections (sepsis) or cancer (including liver cancer).
- You do not have chronic kidney disease or serious heart or lung conditions.
- You are not currently on immunosuppressive medications or pregnant/breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a treatment made from stem cells (cells that can help repair tissues) can improve liver function in people with a sudden worsening of long-term liver disease. The stem cells are given through a vein, and the goal is to see if they help the liver recover without needing a transplant.
This trial tests whether a special type of stem cell therapy can help people with severe liver failure (called ACLF) that is not caused by a virus. The treatment may help your liver recover and improve your overall condition.
This trial tests whether stem cells from donated umbilical cords can help people with acute-on-chronic liver failure, a sudden worsening of chronic liver disease. The goal is to see if this treatment improves liver function and survival.
This trial looks at how well stem cell (MSC) treatment works for people with severe liver failure caused by hepatitis B. It checks what factors affect the success of the treatment.
This trial tests whether a stem cell infusion made from umbilical cord tissue can help people with severe liver failure caused by hepatitis B. The stem cells may reduce liver damage and improve recovery.
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Hear when a new Acute-On-Chronic Liver Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.