Clinical trials
Liver Failure clinical trials
Below are recruiting liver failure clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07727759Recruiting
CT scan to predict liver failure after surgery
This trial uses special CT scans to create a map of your liver's blood vessels before surgery. The goal is to predict if your liver might fail after part of it is removed, so doctors can better plan your care.
Minya, Minya GovernorateAges 18 years+ - NCT04613921Recruiting
Liver transplant study for severe worsening liver failure
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Los Angeles, CaliforniaAges 18–80 - NCT05170971Recruiting
Fecal transplant trial for worsening liver failure
This trial studies fecal microbiota transplantation (a transfer of healthy gut bacteria from a donor) to help people with worsening liver failure. It may help by changing gut bacteria, which can affect complications like confusion, fluid buildup, infections, and kidney problems.
Ningbo, ZhejiangAges 18–65 - NCT05727722RecruitingPhase 1
Micro-packaged liver cell transplant for adult liver failure
This Phase 1 study tests a new way to place liver cells (in small protective “micro-packages”) inside the belly to treat liver failure. It aims to see whether the treatment is safe and potentially helps liver function in adults with worsening chronic or acute-on-chronic liver failure.
ShanghaiAges 18–65 - NCT05989958RecruitingPhase 1/Phase 2
HepaCure for acute-on-chronic liver failure
This trial tests a new treatment called HepaCure for people with acute-on-chronic liver failure (a sudden worsening of liver function in someone with long-term liver disease). The goal is to see if it is safe and can help improve liver function.
Beijing, Beijing MunicipalityAges 18–65 - NCT06224023Recruiting
Presepsin levels in ascites fluid in liver failure
This study is testing whether a blood test for presepsin (a protein that can show infection) can help predict infection in the belly fluid of people with chronic liver failure and ascites. If you have ascites and liver failure, this trial may help doctors better spot infections early.
BucharestAges 18 years+ - NCT06366048Recruiting
Liver surgery and risk of liver failure study
This study looks at how the amount of healthy liver tissue removed during surgery affects the risk of liver failure after the operation. It is for people with common types of liver cancer (HCC or ICC) who are having a planned liver resection.
Fujian, Shanghai MunicipalityAges Any age - NCT06831643Recruiting
Comparing two types of plasma exchange for children with sudden liver failure
This trial tests whether a higher volume of plasma exchange (cleaning the blood to remove toxins) works better than the standard amount for children with acute liver failure who are not improving with usual care.
New Delhi, National Capital Territory of DelhiAges 3–18 - NCT06904755RecruitingPhase 1
Stem cell therapy for liver failure through blood purification
This trial tests whether adding mesenchymal stem cells to a blood-cleaning procedure helps people with acute liver failure recover. It may reduce inflammation and improve liver function.
Guangzhou, GuangdongAges 18–65 - NCT07053488RecruitingPhase 1/Phase 2
Gene-edited liver transplant to lower rejection risk
This trial tests a liver transplant using a donor organ that has been gene-edited to reduce the risk of rejection. It may help people who need a liver transplant and are not a perfect tissue match with their donor.
Beijing, ChangpingAges 16–85 - NCT07765823Recruiting
N-acetylcysteine for liver failure not caused by acetaminophen
This trial tests whether the drug N-acetylcysteine (NAC) can help people with sudden liver failure that is not caused by acetaminophen (like Tylenol). If you qualify, you may receive NAC, which might help your liver recover.
Lahore, Punjab ProvinceAges 18–60 - NCT03627013RecruitingPhase 3
Compare two transplant fluid solutions for kidney, liver, pancreas
This Phase 3 study compares two types of transplant fluid (Custodiol-N vs Custodiol) to protect organs while they are stored before surgery. It may help by reducing damage to the kidney, liver, or pancreas during transplant preparation.
GrazAges 18 years+ - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT05689645RecruitingPhase 2
Drug trial for liver injury or liver failure
This Phase 2 trial tests an injection medicine (F573) to see if it can improve people with liver injury, drug-related liver damage, or liver failure. You may be screened with blood tests, liver stiffness measurements, and possibly symptom checks.
Beijing, Beijing MunicipalityAges 18–60 - NCT06893042Enrolling by invitation
Study of acute liver failure in children
This trial looks at children with sudden severe liver injury. It tests treatments for acute liver failure to understand how to help them recover.
Guangzhou, GuangdongAges 1 minute–18 years - NCT07585890Recruiting
Liver Transplant Outcomes With Machine Preservation in Europe
This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.
ViennaAges 18 years+ - NCT07312864RecruitingPhase 1/Phase 2
New bioartificial liver for liver failure and small-for-size syndrome
This study tests a new bioartificial liver made from special cells to support people with severe liver problems, including liver failure or when the liver is too small after surgery. It aims to see if it is safe and can help the liver recover.
BeijingAges Any age - NCT07275554Recruiting
Gene patterns and risk prediction in hepatitis B liver failure
This study looks at how gene changes (methylation) in people with hepatitis B-related liver failure may predict how well they will do. It aims to create a risk score to guide treatment.
Jinan, ShandongAges 18 years+ - NCT06908746Recruiting
Citrate Anticoagulation in Dialysis for Liver and Kidney Failure
This trial looks at whether a blood thinner called citrate is safe and effective in patients who have both kidney and liver failure while on continuous dialysis in the ICU. It may help guide treatment for people with serious organ problems.
Edegem, AntwerpAges 18 years+ - NCT05030571Recruiting
Plasma adsorption for adults with liver failure in the ICU
This trial studies a treatment called the Double Plasma Molecular Adsorption System (DPMAS) for people with acute-on-chronic liver failure while they are in the ICU. It aims to see whether filtering certain substances from blood can improve outcomes and safety for critically ill patients.
BangkokAges 18 years+ - NCT06987604Enrolling by invitation
Dialysis intensity for high ammonia in liver failure
This trial tests if a higher intensity of continuous dialysis (CRRT) better lowers ammonia levels in patients with liver failure. It aims to find the best approach to reduce brain complications from high ammonia.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05740696Recruiting
Registry study for managing liver failure in China
This is a study that collects real-world information about people with liver failure or “pre-liver failure.” It aims to help doctors choose the best management approach for patients like you and improve care over time.
Xi'an, ShaanxiAges Any age - NCT05985863RecruitingPhase 1/Phase 2
Stem cell therapy for acute-on-chronic liver failure
This trial tests whether stem cells from donated umbilical cords can help people with acute-on-chronic liver failure, a sudden worsening of chronic liver disease. The goal is to see if this treatment improves liver function and survival.
Beijing, Beijing MunicipalityAges 18–70 - NCT05613010Recruiting
Tech tools to help young transplant patients take meds correctly
This study tests technology (like text reminders and an electronic pill box) to help adolescents and young adults who received a kidney or liver transplant take their medicines every day. It may help protect the transplant by improving medication adherence.
Baltimore, MarylandAges 13–25
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Common questions
- Are there clinical trials for liver failure?
- Yes. Clin2 currently lists 69 recruiting liver failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.