Metoprolol for heart failure with COPD
Part of Lungs & breathing clinical trials.
This trial tests whether a low dose of metoprolol (a beta-blocker) is safe and helpful for people who have both heart failure with reduced pumping ability and COPD. The goal is to see if it can improve heart function without worsening breathing problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have heart failure with reduced ejection fraction (LVEF of 40% or less) and symptoms like shortness of breath or fatigue (NYHA class II–IV).
- Your heart failure is caused by blocked arteries (ischemic heart disease) or a weakened heart muscle (dilated cardiomyopathy).
- You have COPD that is moderate or worse, meaning a lung test shows your FEV1/FVC ratio is less than 0.7 and your FEV1 is less than 80% of normal.
- You are not currently taking more than 23.75 mg of metoprolol per day.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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