Arm-cuff therapy to protect the brain during aneurysm coiling
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether a gentle arm-cuff therapy (ischemic conditioning) may help reduce risk of small brain injuries after stent-assisted coiling for an unruptured aneurysm. Participants receive standard coiling plus the arm-cuff therapy during the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You need to be between 18 and 80 years old.
- You must have an unruptured brain aneurysm that your doctor plans to treat with stent-assisted coiling (a procedure using a small tube and a mesh-like stent).
- You must be willing to receive the ischemic adaptation therapy (a gentle, repeated blood-pressure cuff procedure on your arm).
- You cannot have certain other brain blood vessel conditions (like arteriovenous malformations or moyamoya disease), or a history of bleeding strokes.
- You cannot be pregnant, have had a heart attack in the last month, or have advanced kidney disease.
- You must have healthy, normal arms: no significant circulation problems, nerve damage, arm injury, or severe narrowing of a major arm artery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a simple, non-invasive treatment called remote ischemic conditioning (briefly inflating and deflating a blood pressure cuff on your arm) can improve the safety and effectiveness of surgery for a chronically blocked carotid artery. It may help protect your brain during and after the procedure.
This study tests whether a simple, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff to briefly squeeze the arm or leg) can help improve recovery after bleeding in the brain from a burst aneurysm. The treatment is given after the aneurysm has been secured, and may help reduce brain damage and improve outcomes.
This trial tests a safe, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your leg) to see if it helps brain recovery after aneurysm surgery. It might reduce secondary damage and improve outcomes.
This trial tests a simple, non-drug treatment called remote ischemic conditioning (repeatedly inflating and deflating a blood pressure cuff on an arm) to see if it can help people who have both a recent stroke and signs of heart injury. The goal is to help protect the heart and improve recovery after a stroke.
This trial tests whether a simple, non-drug treatment (using a blood pressure cuff to briefly restrict blood flow to your arm) can help people with a recent moderate stroke in the back part of the brain. It aims to improve recovery by preparing the body to better handle the stroke damage.
This study tests whether using a blood pressure cuff on the arm to temporarily restrict blood flow (remote ischemic conditioning) can help people recover after a brain bleed from a ruptured aneurysm. It may reduce damage and improve outcomes.
Hear when a new Unruptured Intracranial Aneurysm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.