Clin2
NCT06829173Possibly a fitRecruiting

Testing a new drug with radiation for aggressive brain tumors

High-Grade Glioma

Part of Cancer clinical trials.

This trial tests a new oral drug called XRD-0394 given together with radiation therapy for people with high-grade glioma, a type of aggressive brain tumor. The goal is to see if adding this drug makes radiation more effective.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
39 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have a high-grade glioma (a fast-growing brain tumor), confirmed by a biopsy or imaging.
  • Your liver and kidney function are within safe limits for the study.
  • You are able to care for yourself (ECOG performance status 0-2).
  • If you are of childbearing potential, you agree to use highly effective birth control during the study.
  • You have not had radiation to the same brain area before (for newly diagnosed patients) or your tumor has come back and it's been at least 3 months since your last brain radiation.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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