Nasal spray treatment to reduce mild sleep apnea congestion
Part of Brain & nervous system, Lungs & breathing clinical trials.
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 to 65 years old.
- You’ve had daily nasal congestion for at least 1 year (allergic or non-allergic rhinitis).
- You’ve been using the maximum recommended dose of a nasal corticosteroid spray for at least 1 month.
- Your sleep study shows mild obstructive sleep apnea (AHI between 5 and 15) and oxygen levels stay at least 88%.
- Your nasal congestion is moderate to severe based on daily/weekly symptom ratings before the study starts.
- You can sign the consent form and follow study visits and instructions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether certain medications can help older adults with mild to moderate sleep apnea breathe better during sleep. It aims to improve sleep quality and safety for elderly patients.
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
This study compares two types of allergy-related nasal treatment: a rinse with azelastine and mometasone versus standard nasal sprays. It aims to see which approach works better for people with long-term (chronic) rhinitis over 6 months.
This study tests whether a nasal decongestant spray can help prevent breathing problems during anesthesia for children with a cold. If your child has a recent cold and is having surgery, this could help make the anesthesia safer.
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
This trial tests if an investigational nasal spray (ETH47) can reduce asthma symptoms triggered by a common cold virus (rhinovirus). You will be exposed to the virus in a safe setting to see if the spray helps control your asthma.
Hear when a new Sleep Apnea trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.