Clinical trials
Nasal Obstruction clinical trials
Below are recruiting nasal obstruction clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05920330Recruiting
Study of blocked noses and loss of smell
This study looks at people who have trouble smelling and also feel their nose is blocked. The researchers want to understand what causes these symptoms and how they might be related, which could guide better treatment.
Columbus, OhioAges 18–70 - NCT06830109RecruitingPhase 2
Testing a nasal spray for stuffy nose relief
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
St Louis, MissouriAges 18 years+ - NCT07379775Recruiting
Testing AAR for nasal obstruction surgery decisions
This trial tests whether a simple device that measures your breathing (AAR) is reliable enough to help doctors decide if surgery is needed for nasal obstruction. It looks at patients who already plan to have surgery to see if this test matches what the surgeon finds.
Draguignan, VarAges 18 years+ - NCT05494346Recruiting
Seawater nasal spray with essential oils for blocked nose
This trial tests whether a seawater nasal spray (with essential oils) is safe and works well for people ages 12+ who have sudden (acute) cold- or allergy-related nasal blockage. You may be able to join if you can use the spray as instructed and complete simple monitoring and questionnaires.
Blainville-sur-OrneAges 12 years+ - NCT06580210Recruiting
Seawater spray with essential oils for stuffy nose
This trial tests a seawater and essential oil spray to clear a stuffy nose caused by a cold, sinus infection or allergies. The spray is meant to help you breathe easier without strong medicines.
BayeuxAges 12 years+ - NCT05287841Recruiting
Battten graft during septum and turbinate surgery
This study tests whether adding a “batten graft” during septoplasty and turbinate reduction improves nasal breathing and nasal airflow. It aims to see if the graft helps when breathing blockage is mainly from the septum, enlarged turbinates, and the outside nasal valve collapsing.
Poplar Bluff, MissouriAges 18 years+ - NCT04194216Enrolling by invitationPhase 3
Antibiotic prevention during rhinoplasty surgery
This trial studies whether giving antibiotics before and around rhinoplasty (nose reshaping) can lower the risk of infection. If you qualify, you may be randomized to receive antibiotic prevention or another approach to prevention.
Stanford, CaliforniaAges 18 years+ - NCT06670261Recruiting
Testing a new way to diagnose breathing problems
This study uses computer modeling to understand nasal breathing. It compares people without nasal symptoms and those with chronic nasal blockage from a deviated septum, to see if modeling can help diagnose the cause.
BordeauxAges 18–69 - NCT07626437RecruitingPhase 3
Cold and Flu Symptom Relief Medicine Trial
This study tests a combination medicine containing pain reliever, caffeine, and allergy medication to help ease nasal congestion and other cold or flu symptoms. You'd take the medicine for a short period and report how well it works.
Belo Horizonte, Minas GeraisAges 18–60 - NCT06614582Enrolling by invitation
Long-term nose tube study for children with weak muscle tone
This study looks at the long-term safety and effectiveness of a nose tube (nasopharyngeal airway) for children who have obstructive sleep apnea due to weak muscle tone. It's for children who already used this device in a previous study.
Ann Arbor, MichiganAges 3–23 - NCT07531810Recruiting
Nose Surgery Recovery and Patient Satisfaction Study
This study tracks how patients feel and function after nose surgery that uses a piece of cartilage (septal extension graft) to reshape the nose. Researchers want to understand both the benefits and any complications to improve future care.
Sivas, SivasAges 18 years+ - NCT05527652Recruiting
Breathing tube device to help blocked upper airways in children
This study tests a self-supporting breathing tube placed through the nose during sleep to reduce upper airway blockage and improve breathing in children. It may help children who have sleep apnea symptoms, especially after tonsil/adenoid treatment or when tonsil removal isn’t possible.
Ann Arbor, MichiganAges 3–21 - NCT03725956Recruiting
Sleep study before and after nasal polyp surgery
This study uses a sleep test to look at breathing and sleep patterns in people with nasal polyps who need surgery because medicine didn’t help. It may help doctors understand how nasal polyps affect sleep and how surgery changes those sleep measurements.
LilleAges 18 years+ - NCT02630121RecruitingPhase 4
Nasal spray treatment to reduce mild sleep apnea congestion
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Tampa, FloridaAges 18–65 - NCT07025304Recruiting
Study of REFLEX ULTRA 45 for nasal turbinate reduction in China
This trial tests a new device called REFLEX ULTRA 45 that uses radiofrequency energy to shrink the nasal turbinates (the fleshy shelves inside your nose) to help you breathe easier. It is for people with long-term nasal stuffiness who have not gotten relief from nasal sprays.
Guangzhou, GuangdongAges 18–65 - NCT03925389Recruiting
Analyzing results after external septorhinoplasty for breathing issues
This trial looks at how well an external septorhinoplasty (surgery to improve the nasal passage) works for people with long-term nasal blockage. It mainly involves filling out questionnaires so the researchers can analyze outcomes over time.
AntwerpAges 18 years+ - NCT04190953Recruiting
Braces and expanders in kids to improve airflow space
This study looks at how jaw and palate treatments affect airflow through the upper airway in children with a specific bite and jaw shape. It may help researchers understand which treatments improve space for breathing and related pressure changes.
Edmonton, AlbertaAges 8–14 - NCT06944925RecruitingPhase 1
Study of BBT002 for COPD and Nasal Polyps
This trial tests a new drug, BBT002, first in healthy volunteers and then in people with chronic obstructive pulmonary disease (COPD) or chronic sinusitis with nasal polyps. It aims to see if the drug is safe and how it works in the body.
Bowling Green, KentuckyAges 18–80 - NCT05974488Recruiting
Using a throat airway to help oxygen during TEE
This study tests whether placing a specific airway device in the lower throat can improve oxygen levels while you get a TEE (a heart ultrasound done through the throat). It may help make the procedure safer and more comfortable for some people, compared with standard care.
Miami, FloridaAges 18 years+ - NCT06570629Recruiting
Fixing air leaks with nasal CPAP
This trial looks at ways to fix air leaks that happen when using a CPAP mask at night. It may help if you have sleep apnea and your CPAP is leaking a lot despite using a nasal mask.
São Paulo, BrazilAges 18 years+ - NCT07307560Recruiting
High-flow oxygen during sedation for sleep apnea patients having endoscopy
This study tests if high-flow nasal oxygen can prevent oxygen drops during sedated endoscopy in patients with severe obstructive sleep apnea. It may help people who are at higher risk of breathing problems during the procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT07222410Recruiting
Smart oxygen control for COPD patients on nasal high flow
This trial tests a smart oxygen system that automatically adjusts oxygen levels for people with COPD who are in the hospital using a nasal high-flow device. It may help keep your oxygen levels stable without needing constant adjustments.
Birmingham, AlabamaAges 22 years+ - NCT06570616Recruiting
Reducing mask leaks during CPAP for sleep apnea
This study tests a method to help CPAP users with nasal masks who have high air leaks. It aims to find better ways to reduce unintentional leaking so treatment works more effectively.
São Paulo, BrazilAges 18 years+ - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+
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Nasal Obstruction trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for nasal obstruction?
- Yes. Clin2 currently lists 27 recruiting nasal obstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nasal obstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nasal obstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.