Inhaled steroid to prevent lung inflammation from returning after immunotherapy
Part of Infections, Lungs & breathing clinical trials.
This trial tests whether using an inhaled steroid (budesonide) can help prevent lung inflammation (pneumonitis) from coming back in people who have had it caused by immunotherapy cancer treatment. It may be an option for patients who need extra support after their first bout of this side effect.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a confirmed solid tumor cancer and are currently receiving immunotherapy.
- You have had a first diagnosis of immunotherapy-related lung inflammation (pneumonitis) that was grade 2 or higher, and you are currently taking steroids by mouth for it.
- You (or a caregiver) can use the budesonide inhaler (Turbuhaler) properly.
- Your overall health (organs like kidneys, liver, heart, and blood sugar) is stable enough, in the doctor's opinion.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a way to treat inflammation of the liver (hepatitis) caused by immune cancer medicines (anti-PD-1/PD-L1, sometimes with anti-CTLA-4) without relying on high-dose steroids. It may help reduce steroid side effects while keeping liver inflammation under control.
This trial tests whether breathing in steroid medicine before and during radiation can lower how often and how badly “radiation lung inflammation” (radiation pneumonitis) happens in people with lung cancer. If you qualify, it may help protect your lungs while you receive radiation with chemotherapy or targeted therapy.
This study tests whether adding a special nutritional supplement to the usual steroid treatment helps people recover from lung inflammation caused by cancer immunotherapy. If you have grade 3-4 immune-related pneumonitis, this trial may offer a way to improve your recovery.
This study tests whether adding an immune-modulating tablet (made from bacteria) to a standard combination inhaler for asthma improves asthma control more than the inhaler alone. The study aims to see if this combination helps reduce symptoms and lung inflammation.
This trial tests if inhaled corticosteroids (ICS) work better for COPD patients with different eosinophil levels. You must already be taking two long-acting bronchodilators and have stopped smoking for at least 6 months.
This trial tests a triple combination inhaler (anti-inflammatory plus two bronchodilators) to see if it can improve lung function in people who are showing early signs of chronic lung damage. It might help if you are a smoker with breathing symptoms and your test shows slightly reduced lung function.
Hear when a new Pneumonitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.