Inhaled steroid to prevent lung inflammation during cancer treatment
Part of Cancer, Injuries & trauma, Lungs & breathing clinical trials.
This trial tests whether breathing in steroid medicine before and during radiation can lower how often and how badly “radiation lung inflammation” (radiation pneumonitis) happens in people with lung cancer. If you qualify, it may help protect your lungs while you receive radiation with chemotherapy or targeted therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have non-small cell lung cancer that cannot be fully removed by surgery (locally advanced or metastatic, stages IIIA/IIIB/IV).
- Your treatment plan includes radiation along with chemotherapy or targeted therapy.
- Your cancer can be measured/checked on scans, and you have an expected survival of more than 4 months.
- Your general condition is fair enough to study participation (ECOG 0–2 or a Karnofsky score of 70–100).
- You can do breathing tests with good inspiratory flow (90 liters/min or higher).
- You have NOT used steroid medicines by mouth or inhaler recently (you must not be taking systemic or inhaled corticosteroids).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a drug called nintedanib to see if it can prevent radiation-related lung inflammation (pneumonia) in people with lung cancer that cannot be surgically removed. It may help protect your lungs during radiation treatment.
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen) can prevent lung inflammation caused by breast cancer radiation. It may help reduce the risk of radiation pneumonitis in certain breast cancer survivors.
This study looks at how radiation therapy for breast cancer may affect your lungs over time. Researchers will measure lung function and see if problems develop, so they can better understand and protect patients.
This study looks at cells from the lungs of people who developed lung inflammation after chest radiation for cancer. It aims to understand why some people get this reaction, which may help find better treatments.
This trial tests whether using an inhaled steroid (budesonide) can help prevent lung inflammation (pneumonitis) from coming back in people who have had it caused by immunotherapy cancer treatment. It may be an option for patients who need extra support after their first bout of this side effect.
This trial tests if using a simple breathing exercise device (called an incentive spirometer) during chemo and radiation for advanced lung cancer can help improve breathing outcomes and overall recovery.
Hear when a new Radiation Pneumonitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.