Liver-directed chemo with standard chemo for breast cancer
Part of Cancer, Skin clinical trials.
This trial tests if giving a high dose of chemotherapy directly into the liver, followed by standard chemotherapy, is safe and works better than standard chemo alone for people with breast cancer that has spread mostly to the liver.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have metastatic breast cancer that is HER2-negative (including triple-negative).
- Your breast cancer is mostly in the liver, and the liver involvement is 50% or less.
- You have tried at least one type of chemotherapy and, if your cancer is hormone-receptor positive, you have also tried hormone therapy and a CDK 4/6 inhibitor.
- You are able to receive at least one of these standard chemotherapies: eribulin, vinorelbine, or capecitabine.
- You have not had prior chemoembolization or radioembolization to the liver.
- You are in good overall health (ECOG 0-1) and weigh at least 35 kg.
- There are no active brain metastases or bleeding problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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