Adding lenvatinib to immunotherapy for liver cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests adding lenvatinib (a targeted therapy pill) to a combination of two immunotherapy drugs (durvalumab and tremelimumab) for people with liver cancer that cannot be removed by surgery. The goal is to see if the three-drug approach works better than the two immunotherapy drugs alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and weigh more than 66 pounds.
- Your liver cancer has not spread to other parts of the body and can be measured on a scan.
- You have not had any previous whole-body treatments for liver cancer.
- Your liver function is good enough (a Child-Pugh score of A or B) and your overall health allows for daily activities (ECOG 0 or 1).
- If you have hepatitis B or C, it must be stable and you may need treatment during the study.
- You are willing to use effective birth control and avoid donating blood for several months after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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