Study of plozasiran for severe high triglycerides with pancreatitis
Part of Hormones & metabolism clinical trials.
This study tests an investigational drug called plozasiran for people with severely high triglycerides that have already caused pancreatitis (inflammation of the pancreas). The goal is to see if the drug can lower triglycerides and help prevent future attacks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a male, or a female who is not pregnant and not planning to become pregnant, and not breastfeeding.
- You have had a blood test showing very high triglycerides (880 mg/dL or higher) at least once in the past.
- You have had at least one episode of pancreatitis (inflammation of the pancreas) in the last 5 years that was not caused by something else.
- You are willing to follow a low-fat diet and keep it stable during the study.
- You are already taking standard medications for high triglycerides, unless you cannot tolerate them or they didn't work for you.
- You do not have serious heart disease, kidney failure, or advanced liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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