Testing tezepelumab for moderate to severe COPD
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 80 years old
- You have had at least 2 moderate COPD flare-ups (needing antibiotics or steroids) or 1 severe flare-up (needing hospital) in the last year
- Your eosinophil count (a type of white blood cell) is 150 or higher on a recent blood test
- You have COPD symptoms that affect your daily life (score 15 or more on a standard questionnaire)
- You are currently using a triple inhaler (steroid + two bronchodilators) or a dual inhaler if triple isn't suitable, for at least 3 months
- You are a former or current smoker with at least a 10 pack-year history (e.g., 1 pack a day for 10 years)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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