Tezepelumab clinical trials

Tezepelumab for peanut allergy oral immunotherapy

This trial tests whether adding tezepelumab (a biologic drug) to peanut oral immunotherapy can help people with peanut allergy better tolerate small amounts of peanut protein without having an allergic reaction.

Testing tezepelumab for kids with severe asthma

This study tests if tezepelumab can help reduce severe asthma attacks in children ages 5 to 11. It compares the drug to a placebo (a dummy treatment) to see if it is safe and effective.

Tezepelumab for Nasal Polyps in Chinese Adults

This study tests whether tezepelumab, a new injectable medicine, can help reduce nasal polyps and improve symptoms like nasal congestion, loss of smell, and sleep problems. You would receive the study drug while continuing your current nasal steroid spray, and your doctors would track how your symptoms change.

Tezepelumab for asthma attacks in the emergency room

This trial tests if a drug called Tezepelumab can help adults with asthma who visit the emergency room. It aims to reduce severe asthma attacks and improve breathing control.

Tezepelumab for moderate to very severe COPD

This study tests a new medication called tezepelumab (given as a shot) to see if it can reduce COPD flare-ups in people with moderate to very severe COPD who have had recent flare-ups despite using inhalers. It may be an option for those with higher levels of eosinophils (a type of white blood cell) in their blood.

Testing tezepelumab for moderate to severe COPD

This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.

Tezepelumab for severe asthma

This study tests a drug called tezepelumab for people with severe asthma that is not well controlled with current treatments. It aims to see if adding this drug can reduce asthma attacks and improve symptoms.

Efficacy of an Anti-TSLP Monoclonal Antibody in the Management of Chronic Bronchial Disease Induced by Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Stem Cells Transplantation Recipients

Physical activity study for people with severe asthma starting tezepelumab

This study tests whether a physical activity program can help people with severe asthma achieve better control and reduce flare-ups when added to a new treatment called tezepelumab.

Tezepelumab for chronic sinusitis with nasal polyps in Russia

This study tracks how well tezepelumab works for people with chronic sinusitis and nasal polyps in real-world settings. It aims to see if this medication reduces symptoms and the need for surgery.

Real-world study of tezepelumab for chronic nasal polyps

This study follows patients with chronic rhinosinusitis with nasal polyps (CRSwNP)—a condition causing blocked sinuses and nasal growths—who are starting a new biologic medication called tezepelumab. Researchers will track how symptoms and quality of life improve over time in everyday medical practice.

Lowering inhaled steroids for tezepelumab-treated asthma patients

This trial looks at whether people with severe asthma who are taking the biologic tezepelumab can safely reduce their use of inhaled corticosteroids (ICS). It aims to see if reducing or stopping ICS affects asthma symptoms or flare-ups.

Drug that blocks TSLP to reduce COPD flare airway inflammation

This Phase 2 trial tests whether blocking TSLP can reduce inflammation in the airways of people with COPD, especially around flare-ups. If you often need prednisone and/or antibiotics for COPD exacerbations, this study may help determine a new treatment approach.

Tezspire heart safety study

This study looks at whether the asthma medicine Tezspire (tezepelumab) affects the risk of heart problems compared to other standard treatments for severe asthma. It will help doctors understand if Tezspire is safe for your heart.