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NCT06898437Possibly a fitRecruiting

Lutetium-177 LNC1004 for advanced thyroid cancer that no longer responds to standard treatments

Radioiodine Refractory Differentiated Thyroid Cancer

Part of Cancer, Hormones & metabolism clinical trials.

This trial tests a radioactive drug called 177Lu-LNC1004 for people with a type of thyroid cancer that is no longer responding to standard treatments. The drug targets a protein called FAP found on tumor cells, which may help shrink tumors and slow disease progression.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
20 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You have a type of thyroid cancer that no longer responds to radioactive iodine and standard therapies like TKI drugs, or you have chosen not to take these therapies.
  • You are in fairly good overall health (able to care for yourself most days).
  • You have at least one tumor that can be measured on a scan.
  • Your tumor shows high levels of the FAP protein on a special PET/CT scan.
  • Your blood counts and organ function (kidney, liver) are within acceptable ranges.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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