Imaging for early heart failure with stiff heart muscle (HFpEF)
Treatments studied
Part of Heart & circulation clinical trials.
This study uses advanced imaging to find early signs of a type of heart failure where the heart pumps well but doesn't relax properly (HFpEF). It may help if you have shortness of breath and a slightly enlarged heart chamber but don't yet have a clear heart failure diagnosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old.
- You get short of breath when you exert yourself.
- A blood test shows a high NT-proBNP level (a sign of heart strain).
- An ultrasound of your heart shows an enlarged left upper chamber but no other heart failure changes.
- You do not have atrial fibrillation, a history of heart failure with reduced pumping ability, or current chest pain.
- You are not allergic to or currently taking SGLT2 inhibitors (a type of diabetes medicine).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether fat around the heart affects a type of heart failure where the heart pumps well but is stiff (HFpEF). You may be able to join if you have this condition, are 18 or older, and can understand English.
This trial studies people who have heart failure symptoms but whose heart pumping strength is largely preserved. It aims to better understand this specific type of heart failure and how best to treat or evaluate it.
This study looks at people with a type of heart failure where the heart pumps normally but still doesn't fill properly. Researchers are using ultrasound pictures of the heart (echocardiograms) and blood tests to better understand this condition and find better ways to treat it.
This study looks for people who may have heart failure with preserved pumping function, where the heart is stiff and doesn't fill properly. It aims to better understand and identify this condition to improve care.
This trial uses a special heart MRI to create pressure-volume loops in people with heart failure who have a normal pumping strength (ejection fraction of 50% or higher). It aims to better understand heart function and could help guide future treatments. You may qualify if you have heart failure symptoms and specific heart structure or function changes.
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
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