Testing imaging to study heart symptoms without blocked arteries
Part of Heart & circulation clinical trials.
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 and can sign an informed consent form
- You are having a heart catheter test (coronary angiography) for suspected ischemia (reduced blood flow) and do not have major obstructive coronary artery disease
- Your heart pumping function is preserved, with ejection fraction (EF) 45% or higher
- You can safely do a heart MRI: no metal devices in your chest, no severe claustrophobia, and no history of angioedema
- You should not have very poor or worsening kidney function (GFR below 40 or recent acute kidney injury)
- You can receive the needed medicines and contrast: no allergies to adenosine or related drugs, and no allergy to gadolinium contrast
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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